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Kaplan-Meier overall survival analyses of low and high CD4, CD8A, CD8B, ADGRE1, and IL-6 expression in the tumors of TNBC patients based on DNA microarray data. CD4 low: n = 436; CD4 high: n = 430; CD8A low: n = 434; CD8A high: n = 432; CD8B low: n = 457; CD8B high: n = 409; ADGRE1 low: n = 140; ADGRE1 high: n = 34; IL6 low: n = 469; IL6 high: n = 463.

Journal: Materials Today Bio

Article Title: Empowering chemotherapy-induced antitumor immunity by multi-targeted synergistic combination nanomedicine for triple-negative breast cancer

doi: 10.1016/j.mtbio.2025.102445

Figure Lengend Snippet: Kaplan-Meier overall survival analyses of low and high CD4, CD8A, CD8B, ADGRE1, and IL-6 expression in the tumors of TNBC patients based on DNA microarray data. CD4 low: n = 436; CD4 high: n = 430; CD8A low: n = 434; CD8A high: n = 432; CD8B low: n = 457; CD8B high: n = 409; ADGRE1 low: n = 140; ADGRE1 high: n = 34; IL6 low: n = 469; IL6 high: n = 463.

Article Snippet: The gene expression profiles are generated through standardized DNA microarray analysis procedures, which involve RNA extraction from tumor samples, reverse transcription to cDNA, hybridization to oligonucleotide microarray chips (e.g., Affymetrix U133A or U133 Plus 2.0), followed by fluorescence-based signal detection and normalization using algorithms such as RMA or MAS5 [ ].

Techniques: Expressing, Microarray